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Cisplatin blocks depolarization-induced calcium entry in isolated cochlear outer hair cells

✍ Scribed by Saito, Takehisa; Moataz, Rachida; Dulon, Didier


Book ID
123102516
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
592 KB
Volume
56
Category
Article
ISSN
0378-5955

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Aminoglycoside antibiotics impair calciu
✍ D. Dulon; G. Zajic; J.-M. Aran; Dr. J. Schacht πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 907 KB

Cochlear outer hair cells have been well established as primary targets of the ototoxic actions of aminoglycoside antibiotics. These cells, isolated from the guinea pig cochlea and maintained in short-term culture, were used as a model for evaluating the acute effects of gentamicin on cell viability