## Ceratospongamide, cyclo(-Ile-Oxz-Phe-Pro-Thz-Phe-Pro-) (Oxz = oxazoline and Thz = thiazole), C 41 H 49 N 7 O 6 S, is a thiazole-containing cyclic peptide isolated from marine sources. Two stable isomers are known and the structure of the cis,cis-isomer has been determined. The peptide ring is f
cis,cis-Ceratospongamide monohydrate
✍ Scribed by Doi, Mitsunobu ;Asano, Akiko
- Publisher
- International Union of Crystallography
- Year
- 2002
- Tongue
- English
- Weight
- 422 KB
- Volume
- 58
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
Single-crystal X-ray study T = 100 K Mean '(C±C) = 0.006 A Ê R factor = 0.056 wR factor = 0.141 Data-to-parameter ratio = 16.4
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80 "C/0.003 Torr; UV-Spektrum (in n-Hexan): 302 (4.17), 270 (4.12), 260 (4.06) nm (log E ) ; NMR-Spektrum (in CDC13): Dublett zentriert bei 7 = 7.34 (4CH3). Multipletts zentriert bei T = 6.17 (H-3a, H-7a), bei 4.55 (H-2. H-3. H-4, H-5, H-6) und bei 3.65 (H-7)]. Das NMR-Spektrum von (5) erlaubt keine