## Abstract A total of 44 patients with previously untreated Stage IV squamous cell carcinomas of the head and neck were treated with a combination of cis‐platinum (100 mg/sq m) and 96‐hour infusion of 5‐fluorouracil (5‐FU) (1,000 mg/sq m/day) in two courses or with cis‐platinum (100 mg/sq m) and 1
Cis-platinum induction chemotherapy in the multi-modality initial treatment of advanced stage IV carcinoma of the head and neck
✍ Scribed by Steven D. Schaefer; Robert Middleton; Joan Reisch; Eugene P. Frenkel
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 552 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0008-543X
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## Abstract ## Background Trial TAX 324 showed that induction chemotherapy with docetaxel plus cisplatin and 5‐fluorouracil (TPF) compared with cisplatin and 5‐fluorouracil (PF) followed by chemoradiation increases survival and time to progression in squamous cell carcinoma of head and neck (SCCHN
Forty-one patients with unresectable Stage IV head and neck squamous cell carcinoma were treated with combined modality therapy (CM) consisting of induction chemotherapy followed by surgery and/ or radiotherapy (RT). Treatment and survival results are reported and compared to results obtained in tre