𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Cis and trans in site-specific recombination

✍ Scribed by Garry W. Blakely; David J. Sherratt


Book ID
110831794
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
693 KB
Volume
20
Category
Article
ISSN
0950-382X

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Site-specific DNA recombination systems have considerable utility in manipulating DNA and can facilitate many cloning and gene transfer techniques. The ability of a number of recombinases to catalyze efficient DNA recombination in higher eukaryotes has important and exciting consequences for precise

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## Abstract Summary: To explore the function of genes expressed by myelinating cells we have developed a model system that allows for the inducible ablation of predetermined genes in oligodendrocytes and Schwann cells. The Cre/loxP recombination system provides the opportunity to generate tissue‐sp