✦ LIBER ✦

Site-specific recombination: developments and applications

✍ Scribed by Brian Sauer

Book ID: 103978660
Publisher: Elsevier Science
Year: 1994
Tongue: English
Weight: 701 KB
Volume: 5
Category: Article
ISSN: 0958-1669
DOI: 10.1016/0958-1669(94)90068-x

No coin nor oath required. For personal study only.

✦ Synopsis

Site-specific DNA recombination systems have considerable utility in manipulating DNA and can facilitate many cloning and gene transfer techniques. The ability of a number of recombinases to catalyze efficient DNA recombination in higher eukaryotes has important and exciting consequences for precise chromosome and transgene engineering. Exploitation of these recombinases will facilitate the generation of transgenic animal disease models and help elucidate the function of developmental genes.

📜 SIMILAR VOLUMES

Site-specific recombination

✍ Sherratt, David; Arthur, Avril; Dyson, Paul 📂 Article 📅 1981 🏛 Nature Publishing Group 🌐 English ⚖ 368 KB

Site-specific recombination inZea mays

✍ S. Kerbach; H. Lörz; D. Becker 📂 Article 📅 2005 🏛 Springer 🌐 English ⚖ 304 KB

Insect transgenesis by site-specific rec

Insect transgenesis by site-specific recombination

✍ Wimmer, Ernst A 📂 Article 📅 2005 🏛 Nature Publishing Group 🌐 English ⚖ 256 KB

Inducible site-specific recombination in

Inducible site-specific recombination in myelinating cells

✍ Nathalie H. Doerflinger; Wendy B. Macklin; Brian Popko 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 692 KB

## Abstract Summary: To explore the function of genes expressed by myelinating cells we have developed a model system that allows for the inducible ablation of predetermined genes in oligodendrocytes and Schwann cells. The Cre/loxP recombination system provides the opportunity to generate tissue‐sp

Resolving integral questions in site-spe

Resolving integral questions in site-specific recombination

✍ Rice, Phoebe A 📂 Article 📅 2005 🏛 Nature Publishing Group 🌐 English ⚖ 258 KB

Site specific radioiodination of recombi

Site specific radioiodination of recombinant hirudin

✍ A. Tuong; M. Maftouh; C. Picard; M. Gachon 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 624 KB

Recombinant hirudin variant rHV2-Lys47 was radioiodinated using the chloramine-T method. Depending on the reaction pH, the two tyrosine residues, Tyr3 and Tyr63, responded differently to iodination but without change in total iodination yield. Of the incorporated -125 iodine 80% was located on Tyr3