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cis- and trans-Decahydro-1,6-Naphthyridines. Stereoselective Synthesis and Stereochemistry.

โœ Scribed by T. V. Esipova; A. A. Borisenko; G. V. Grishina

Book ID
101998337
Publisher
John Wiley and Sons
Year
2006
Weight
22 KB
Volume
37
Category
Article
ISSN
0931-7597

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โœฆ Synopsis

Abstract

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A stereoselective approach to the synthesis of cis-and trans-3-fluoro-1-phenylcyclobutylamine has been developed. Excellent stereoselectivity was obtained by the reduction of the appropriately substituted cyclobutanone to give either cis-or trans-isomers of 3-hydroxyl-1-phenylcyclobutylamine, which