(+)-cis-4,5,7a,8,9,10,11,11a-Octahydro-7H-10-methylindolo[1,7-bc][2,6]- naphthyridine: A 5-HT2C/2B Receptor Antagonist with Low 5-HT2A Receptor Affinity
โ Scribed by Nozulak, Joachim; Kalkman, Hans O.; Floerscheim, Philipp; Hoyer, Daniel; Schoeffter, Philipp; Buerki, Hans R.
- Book ID
- 121372122
- Publisher
- American Chemical Society
- Year
- 1995
- Tongue
- English
- Weight
- 763 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0022-2623
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๐ SIMILAR VOLUMES
Novel 7-phenylsulfanyl-1,2,3,4,10,10a-hexahydro-pyrazino[1,2-a] indoles are synthesized using a sixstep protocol. Notably, the synthesis route make use of a new and improved ring-closing methodology for the assembly of the hexahydro-pyrazino[1,2-a]indole scaffold, which is based on intramolecular C
## Abstract A variety of novel 7โsulfanylpyrazinoindole derivatives (V) (11 examples) is synthesized using a new and improved ringโclosing methodology for the assembly of the hexahydropyrazinol[1,2โฮฑ]indole scaffold.