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Cirrhosis pathogenesis: Polymorphism of glutathione S-transferase genes

✍ Scribed by I. A. Goncharova; M. I. Rachkovskii; E. V. Beloborodova; H. Gamal Abd El-Aziz Nasar; V. P. Puzyrev

Book ID
110174802
Publisher
SP MAIK Nauka/Interperiodica
Year
2010
Tongue
English
Weight
201 KB
Volume
44
Category
Article
ISSN
0026-8933

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## Abstract ## BACKGROUND. Pancreatic cancer is a multifactorial disease with metastasis‐prone and therapy‐resistant nature. The authors hypothesized that genetic variants of glutathione S‐transferase (GST) affect detoxification of carcinogens and anticancer agents in the human pancreas and, thus,