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Circulation insulin-like growth factor peptides and colorectal cancer risk: an updated systematic review and meta-analysis

✍ Scribed by Feng Chi, Rong Wu, Yue-can Zeng, Rui Xing, Yang Liu


Book ID
120751547
Publisher
Springer
Year
2012
Tongue
English
Weight
408 KB
Volume
40
Category
Article
ISSN
0301-4851

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## Abstract Insulin‐like growth factors (IGF‐I, IGF‐II) and their binding proteins (IGFBP‐1–6) play a key role in cell proliferation, differentiation and apoptosis, suggesting possible involvement in carcinogenesis. Several epidemiological studies show associations of IGFs with prostate cancer. We