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Circulating gastrin and insulin-like growth factor (IGF-I) and risk of colorectal cancer

✍ Scribed by Paterson, Adrienne C.; Bach, Leon A.; Baldwin, Graham S.; Leeding, Kerri S.; Macrae, Finlay A.; Pizzey, Cathy; Shulkes, Arthur

Book ID
124145358
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
181 KB
Volume
120
Category
Article
ISSN
0016-5085

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## Abstract Insulin‐like growth factor (IGF)‐I, a mitogenic and anti‐apoptotic peptide, has been implicated in the development of several cancers. We hypothesized that high circulating IGF‐I concentrations may be associated with an increased risk of ovarian cancer. A case–control study was nested w