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Circulating vitamin D and colorectal adenomas in Japanese men

✍ Scribed by Ryota Takahashi; Tetsuya Mizoue; Toshie Otake; Jin Fukumoto; Osamu Tajima; Shinji Tabata; Hiroshi Abe; Keizo Ohnaka; Suminori Kono

Book ID: 108586739
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 192 KB
Volume: 101
Category: Article
ISSN: 1347-9032
DOI: 10.1111/j.1349-7006.2010.01575.x

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## Abstract Vitamin D receptor (VDR) activation inhibits proliferation and angiogenesis in the colorectal epithelium, and inhibits metastasis of colorectal tumors. Polymorphisms in the __VDR__ gene alter receptor cellular levels and functioning, and may confer altered susceptibility to colorectal n