Circulating Neutrophils and Liver Injury in Rat Models of Experimental Alcoholic Liver Disease
β Scribed by Aron D. Ross; Victor Saldivia; Betzavel Oporto; Frederick J. Carmichael; Ross Cameron; Yedy Israel
- Book ID
- 109119952
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 529 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0145-6008
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π SIMILAR VOLUMES
Alcoholic hepatitis is characterized by hepatocyte necrosis associated with infiltration of the liver parenchyma by neutrophils. The mechanisms responsible for recruiting neutrophils to the liver are unknown. We report high circulating levels and tissue expression of the endothelial adhesion molecul
Long-term ethanol feeding has been shown to selectively reduce hepatic mitochondrial glutathione content by impairing mitochondrial uptake of this thiol. In this study, we assessed the role of this defect in evolution of alcoholic liver disease by examining the mitochondrial glutathione pool and lip