๐”– Bobbio Scriptorium
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Circulating immune complexes: Their biologic and clinical significance

โœ Scribed by BARNETT, E


Book ID
119058168
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
914 KB
Volume
78
Category
Article
ISSN
1097-6825

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## Abstract Serum circulating immune complexes (CIC) were repeatedly measured by means of the Cl binding assay (Cba) and the Raji cell assay (Rca) in 158 patients with metastatic breast cancer (mbc). Frequency of occurrence and levels of CIC were only slightly increased in mbc when compared to ageโ€

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Studies i n experimental animals have shown t h a t c i r c u l a t i n g , l a r g e -l a t t i c e d immune complexes c o n t a i n i n g IgG antibodies a r e e f f e c t i v e l y removed by Kupffer c e l l s . The removal of immune complexes i s a l s o i n f l uenced by the nature o f antigens