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Circular dichroic investigations into binding of sulfonamides to serum albumin

โœ Scribed by Otagiri, M. ;Nakamura, H. ;Imamura, Y. ;Matsumoto, U.


Book ID
105414636
Publisher
Springer
Year
1989
Tongue
Dutch
Weight
444 KB
Volume
11
Category
Article
ISSN
1573-739X

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โœ Carlo Bertucci; Barbara Nanni; Piero Salvadori ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 155 KB ๐Ÿ‘ 2 views

The reversible binding of ethacrynic acid was characterized by a difference circular dichroism method. A 2/1 stoichiometry was determined for the [drug]/[HSA] (human serum albumin) complex. The reversible binding of ethacrynic acid to HSA determines direct competition with ligands that selectivity b