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Circadian expression of FGF21 is induced by PPARα activation in the mouse liver

✍ Scribed by Katsutaka Oishi; Daisuke Uchida; Norio Ishida


Book ID
113621020
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
102 KB
Volume
582
Category
Article
ISSN
0014-5793

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The Circulating Metabolic Regulator FGF2
✍ Cecilia Gälman; Tomas Lundåsen; Alexei Kharitonenkov; Holly A. Bina; Mats Erikss 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 454 KB

FGF21 is a critical metabolic regulator, pivotal for fasting adaptation and directly regulated by PPARalpha in rodents. However, the physiological role of FGF21 in man is not yet defined and was investigated in our study. Serum FGF21 varied 250-fold among 76 healthy individuals and did not relate to