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Cinepazide maleate protects PC12 cells against oxygen–glucose deprivation-induced injury

✍ Scribed by Zhao, Jun; Bai, Ya; Zhang, Chen; Zhang, Xiao; Zhang, Yun-Xia; Chen, Jing; Xiong, Lize; Shi, Ming; Zhao, Gang

Book ID
125351896
Publisher
Springer Milan
Year
2013
Tongue
English
Weight
648 KB
Volume
35
Category
Article
ISSN
1590-1874

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In our in vitro model, rasagiline a selective irreversible monoamine oxidase-B (MAO-B) inhibitor, protected nerve growth factor (NGF)-differentiated PC12 cells from cell death under oxygen and glucose deprivation (OGD). The severity of the OGD insult, as expressed by cell death, was time-dependent.