Mebudipine and dibudipine protect PC12 cells against oxygen–glucose deprivation and glutamate-induced cell death
✍ Scribed by Nahid Rahbar-Roshandel; Lili Razavi; Bahareh Tavakoli-Far; Massoud Mahmoudian
- Book ID
- 119343413
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 432 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0928-4680
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In our in vitro model, rasagiline a selective irreversible monoamine oxidase-B (MAO-B) inhibitor, protected nerve growth factor (NGF)-differentiated PC12 cells from cell death under oxygen and glucose deprivation (OGD). The severity of the OGD insult, as expressed by cell death, was time-dependent.