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Cilostazol inhibits matrix invasion and modulates the gene expressions of MMP-9 and TIMP-1 in PMA-differentiated THP-1 cells

✍ Scribed by Shih-Yi Chuang; Su-Hui Yang; Tzi-Ya Chen; Jong-Hwei S. Pang


Book ID
113589501
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
679 KB
Volume
670
Category
Article
ISSN
0014-2999

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## Abstract Matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) are the main determinants of tissue remodeling in both physiological and pathological processes. Metabolic processes, which generate oxidants and antioxidants can be influenced by environmental factors such as electr