CIITA versus IFN-γ induced MHC class II expression in head and neck cancer cells
✍ Scribed by Markus Meissner; Theresa L. Whiteside; Roland Kaufmann; Barbara Seliger
- Book ID
- 106078900
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 323 KB
- Volume
- 301
- Category
- Article
- ISSN
- 0340-3696
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Malignant gliomas (MGs), lethal human central nervous system (CNS) neoplasms, contain tumor infiltrating lymphocytes (TIL). Although MHC class II molecules are frequently detected on MG cells, suggesting that they may be capable of antigen (Ag) presentation to CD4^+^ T cells, deficienci
The major histocompatibility (MHC) class II genes encode cell surface proteins that bind antigenic peptide for presentation to T-cells. The class II proteins are expressed constitutively on B-cells and EBV-transformed B-cells, and are inducible by IFN-y on a wide variety of cell types. Retinoblastom