Endoglin negatively regulates transformi
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J. P. Burke; R. W. G. Watson; J. J. Mulsow; N. G. Docherty; J. C. Coffey; Profes
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Article
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2010
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John Wiley and Sons
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English
⚖ 198 KB
👁 1 views
## Abstract ## Background Fibroblasts isolated from strictures in Crohn's disease (CD) exhibit reduced responsiveness to stimulation with transforming growth factor (TGF) β1. TGF-β1, acting through the smad pathway, is critical to fibroblast-mediated intestinal fibrosis. The membrane glycoprotein,