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Chylomicron remnant induces monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cells through an activation of p38 MAPK

✍ Scribed by K Domoto; T Taniguchi; T Takahashi; S Kawasaki; M Taguchi; Y Matsuo; Y Takahashi; Y Fujioka; Y Ishikawa; M Yokoyama


Book ID
119434340
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
150 KB
Volume
151
Category
Article
ISSN
0021-9150

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PDTC, metal chelating compound, induces
✍ Sung-Kwon Moon; Sun-Young Jung; Yung-Hyun Choi; Young-Choon Lee; Cam Patterson; πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 482 KB πŸ‘ 1 views

Pyrrolidine dithiocarbamate (PDTC), a metal chelating compound, is known to induce cell death in vascular smooth muscle cells (VSMC). However, the molecular mechanism for PDTC-induced VSMC death is not well understood. Addition of PDTC reduced cell growth and DNA synthesis on VSMC in low density con