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Chronotropic and inotropic effects of atrial peptides on the isolated systemic heart ofOctopus vulgaris

✍ Scribed by Claudio Agnisola; Lucio Cariello; Amedeo Santis; Antonio Miralto; Bruno Tota


Publisher
Springer-Verlag
Year
1989
Tongue
English
Weight
438 KB
Volume
158
Category
Article
ISSN
0174-1578

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πŸ“œ SIMILAR VOLUMES


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The actions of exogenous arachidonic acid on the performance of the isolated and perfused systemic heart of Octopus vulgaris (collected in the Bay of Naples in 1992), and the potential of this heart for eicosanoid synthesis are described. Arachidonic acid induces positive chronotropic and inotropic

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ANF, ANF7-28 and atriopeptins (AP1, AP2 and AP3) (10(-11) to 3 x 10(-7) M) induce a relaxant response on the guinea-pig isolated trachea, which is partially potentiated by the enkephalinase inhibitor thiorphan 10(-5) M but is unmodified by epithelium removal. Conversely, these drugs were found to be