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Chronopharmacokinetic Study of Valproic Acid in Man: Comparison of Oral and Rectal Administration

โœ Scribed by Yoshiyama, Yuji; Nakano, Shigeyuki; Ogawa, Nobuya


Book ID
120287626
Publisher
Sage Publications
Year
1989
Tongue
English
Weight
718 KB
Volume
29
Category
Article
ISSN
0091-2700

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First-pass elimination of salicylamide i
โœ A. G. de Boer; D. D. Breimer; J. M. Gubbens-Stibbe; A. Bosma ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 474 KB ๐Ÿ‘ 2 views

In order t o study the avoidance of hepatic first-pass elimination following rectal administration, 500 mg of salicylamide (SAM) were given orally and rectally to man. Plasma SAM concentrations were measurable following oral administration, but following rectal administration SAM concentrations were