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Chronic treatment with antidepressant drugs enhances the excitatory effect of quinpirole on hippocampal neurons in vitro

✍ Scribed by Bijak, M.


Book ID
121884371
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
55 KB
Volume
2
Category
Article
ISSN
0924-977X

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Several lines of evidence (binding studies, reduced responsiveness of brain adenylate cyclase to noradrenergic stimulation, electrophysiological data) indicate that chronic treatment with antidepressant drugs induces subsensitivity of central ]~-adrenergic receptors. We studied the effect of acute (