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Chronic nicotine use blocks haloperidol-induced increase in striatal D2-dopamine receptor density

✍ Scribed by Chandan Prasad; Sally A. Spahn; Hiromasa Ikegami

Book ID
115762389
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
267 KB
Volume
159
Category
Article
ISSN
0006-291X

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πŸ“œ SIMILAR VOLUMES

Chronic haloperidol administration incre
Chronic haloperidol administration increases the density of D2 dopamine receptors in the medial prefrontal cortex of the rat
✍ A. John MacLennan; Stella Atmadja; Nancy Lee; H. C. Fibiger πŸ“‚ Article πŸ“… 1988 πŸ› Springer 🌐 English βš– 299 KB

Rats received haloperidol (1.3-1.5 mg/kg/day) via their drinking water for 21 weeks. At the end of this period the density of D2 dopamine receptors and their affinity for [3H]-spiperone were measured in the striatum and medial prefrontal cortex. The chronic haloperidol treatment increased the densit