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Chronic morphine administration increases the apparent number of α2-adrenergic receptors in rat brain

✍ Scribed by Tallman, John F.; Hamburg, Margaret


Book ID
109723168
Publisher
Nature Publishing Group
Year
1981
Tongue
English
Weight
373 KB
Volume
291
Category
Article
ISSN
0028-0836

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Chronic haloperidol administration incre
✍ A. John MacLennan; Stella Atmadja; Nancy Lee; H. C. Fibiger 📂 Article 📅 1988 🏛 Springer 🌐 English ⚖ 299 KB

Rats received haloperidol (1.3-1.5 mg/kg/day) via their drinking water for 21 weeks. At the end of this period the density of D2 dopamine receptors and their affinity for [3H]-spiperone were measured in the striatum and medial prefrontal cortex. The chronic haloperidol treatment increased the densit