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Chronic intermittent hypoxia and acetaminophen induce synergistic liver injury in mice

โœ Scribed by Vladimir Savransky; Christian Reinke; Jonathan Jun; Shannon Bevans-Fonti; Ashika Nanayakkara; Jianguo Li; Allen C. Myers; Michael S. Torbenson; Vsevolod Y. Polotsky


Book ID
110110052
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
800 KB
Volume
94
Category
Article
ISSN
0958-0670

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Acetaminophen toxicity is the most common cause of acute liver failure in the United States and Europe. Although much is known about the metabolism of acetaminophen, many questions remain regarding the pathogenesis of liver injury. In this study, we examined the role of lipopolysaccharide-binding pr