Chronic autoimmune thrombopenia/neutropenia in a boy with persistent parvovirus B19 infection
β Scribed by Wolfram Scheurlen; Kumudha Ramasubbu; Olga Wachowski; Andrea Hemauer; Susanne Modrow
- Book ID
- 117769404
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 147 KB
- Volume
- 20
- Category
- Article
- ISSN
- 1386-6532
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It is generally thought that parvovirus B19 is stable genetically. Consistently, genetic drift has not been found in patients with persistent B19 infection. In this report, longitudinal genetic changes in NS1 and VP1 gene of B19 isolates from three AIDS patients with persistent B19 infection were st
## Abstract A subset of parvovirus B19 (B19) infected patients retains the infection for years, as defined by detection of B19 DNA in bone marrow. Thus far, analysis of B19βspecific humoral immune responses and viral genome variations has not revealed a mechanism for the absent viral clearance. In