Chromosomes in patients treated with Azathioprine
β Scribed by Elisabeth Ganner; Jane Osment; P. Dittrich; H. Huber
- Publisher
- Springer
- Year
- 1973
- Tongue
- English
- Weight
- 366 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0340-6717
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Background: Nodular regenerative hyperplasia (NRH) is a rare hepatic disorder that may lead to severe portal hypertension. Cases of NRH have been reported in patients receiving thiopurines for inflammatory bowel disease (IBD). Since azathioprine (AZA) is used more and more frequently as a maintenanc
Chromosome lesions detected in lymphocytes from 14 patients previously treated with melphalan. a bifunctional alkylating agent, have been analyzed on R-banded preparations. In comparison to controls, there was no significant increase of chromatid-type lesions, but chromosome-type lesions were quite