𝔖 Bobbio Scriptorium
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Chromosomes, 11q and cancer: a review

✍ Scribed by Koreth, John; Bakkenist, Christopher J.; McGee, James O'D.

Book ID
101223072
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
262 KB
Volume
187
Category
Article
ISSN
0022-3417

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✦ Synopsis

This review aims at providing a general understanding of how the multiple cytogenetic aberrations in cancer cells arise and exemplifies this by considering the specific role of chromosome 11q loci in carcinogenesis. Section I provides a theoretical molecular and structural framework for understanding the cytogenetic aberrations described in cancer. Given this background, Section II describes advances in the identification and localization of cancer susceptibility genes on chromosome 11q, highlighting ongoing areas of investigation.

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