A cDNA library specific for mRNA over-expressed in prostate cancer was generated by subtractive hybridization of transcripts originating from prostatic hyperplasia and cancer tissues. cDNA encoding ribosomal proteins L4, L5, L7a, L23a, L30, L37, S14 and S18 was found to be present among 100 analyzed
✦ LIBER ✦
5q11, 8p11, and 10q22 are recurrent chromosomal breakpoints in prostate cancer cell lines
✍ Scribed by Yi Pan; Weng-Onn Lui; Nina Nupponen; Catharina Larsson; Jorma Isola; Tapio Visakorpi; Ulf S.R. Bergerheim; Soili Kytölä
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 219 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1045-2257
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## Background: The presence and possible role of androgen-metabolizing enzymes in androgen-independent prostate carcinoma (cap) are still unclear. the aim of the present study was: 1) to evaluate the pattern of androgen metabolism (relative production of 5alpha-reduced vs. 17-keto androgens); and 2