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Chromosome studies in 2136 couples with spontaneous abortions

✍ Scribed by G. Bourrouillou; P. Colombies; N. Dastugue

Publisher
Springer
Year
1986
Tongue
English
Weight
273 KB
Volume
74
Category
Article
ISSN
0340-6717

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Several cytogenetic studies have reported an increased frequency of aneuploidy in peripheral blood cultures of couples with multiple spontaneous abortions. However, in none of the studies have the chromosome constitutions of the fetuses been known, making it difficult to interpret these observations

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Data are presented confirming that placental chromosome abnormalities are more important than fetal chromosome abnormalities in determining fetal loss. Improved methodologies for studying chromosome abnormalities in spontaneous abortion (SAB) are presented that include results for 141 cases (gestati