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Chromosome findings in effusions from patients with Hodgkin's disease

✍ Scribed by Dieter K. Hossfeld; Carl G. Schmidt

Publisher: John Wiley and Sons
Year: 1978
Tongue: French
Weight: 727 KB
Volume: 21
Category: Article
ISSN: 0020-7136
DOI: 10.1002/ijc.2910210204

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Effusion cells from six patients with advanced Hodgkin's disease were studied. Even though no Hodgkin or Reed‐Sternberg cells could be identified cytologically in five of the six cases, striking chromosome anomalies of a clonal nature, including a number of recurrent marker chromosomes, were demonstrated in all effusions. It is concluded that the effusion cells with abnormal karyotypes were intimately related to the pathogenesis of Hodgkin's disease.

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