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Chromosome-breaking ability of arecoline, a major betel-nut alkaloid, in mouse bone-marrow cells in vivo

✍ Scribed by G.B. Panigrahi; A.R. Rao


Book ID
113254118
Publisher
Elsevier Science
Year
1982
Weight
464 KB
Volume
103
Category
Article
ISSN
0165-7992

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The frequency of chromatid breaks associated with sister chromatid exchanges at the break point was determined in rat bone marrow cells treated in vivo with 7-12 DMBA, during the late S phase of the cell cycle. The chromosomal aberrations and SCEs were scored in the same cells. Under the experimenta