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Chromosome breakage syndromes and cancer

✍ Scribed by Duker, Nahum J.

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
74 KB
Volume
115
Category
Article
ISSN
0148-7299

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We report on a newborn girl with Dubowitz syndrome (DS) and embryonal rhabdomyosarcoma (ERMS), with multiple chromosomal breakage (MCB). The tumor was resected but recurred in a few months, resulting in the infant's death. Malignancy and chromosomal breakage have been reported previously in DS. Howe