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Chromosome break points in clonal and nonclonal chromosome changes in human chronic lymphocytic leukemia

✍ Scribed by KIRSI AUTIO; JIM SCHRODER

Book ID
114808918
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
367 KB
Volume
97
Category
Article
ISSN
0018-0661

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We performed cytogenetic analyses of peripheral blood lymphocytes from 82 Midwestern B-cell chronic lymphocytic leukemia (B-CLL) patients. The cells were cultured with mitogens for 3 4 days. At least I 5 metaphase cells were analyzed in 79 (96%) cases. Fifty (63%) of the 79 patients had clonal chrom