Clonal chromosome abnormalities in chronic lymphocytic leukemia patients revealed by TPA stimulation of whole blood cultures
β Scribed by Fiona M. Ross; George Stockdill
- Book ID
- 119103537
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 669 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0165-4608
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π SIMILAR VOLUMES
We performed cytogenetic analyses of peripheral blood lymphocytes from 82 Midwestern B-cell chronic lymphocytic leukemia (B-CLL) patients. The cells were cultured with mitogens for 3 4 days. At least I 5 metaphase cells were analyzed in 79 (96%) cases. Fifty (63%) of the 79 patients had clonal chrom
## Abstract We performed a multicentric study to assess the impact of two different culture procedures on the detection of chromosomal abnormalities in 217 consecutive unselected cases with chronic lymphocytic leukemia (CLL) referred for routine analysis either at the time of diagnosis (__n__ = 172