## Abstract Cytogenetic studies of eight meningiomas in young children or adolescents were performed. Two tumors exhibited normal karyotypes. Two tumors from patients with bilateral acoustic neurofibromatosis demonstrated monosomy 22 as the only abnormality. Four patients had more complicated karyo
Chromosome abnormalities in multiple meningiomas of a child
✍ Scribed by Dr. Bernd Wullich; Lothar Mayfrank; Karl Schwechheimer; Jürgen Finke; Werner Schempp
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 228 KB
- Volume
- 2
- Category
- Article
- ISSN
- 1045-2257
No coin nor oath required. For personal study only.
✦ Synopsis
We report the cytogenetic findings in two meningiomas from a child presenting with multiple meningiomas. In contrast to the chromosomal profile of adult meningiomas, both tumors studied revealed excess of chromosomes in addition to monosomy 22. This difference is remarkable considering several reports indicating that childhood meningiomas behave differently and have a worse prognosis than those in adults.
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