Chromosome abnormalities in chronic lymphocytic leukemia revealed by cytochalasin B and Epstein-Barr virus
β Scribed by Peter E. Crossen; Joan M. Godwin; David C. Heaton; Sandra M. Tully
- Book ID
- 119103720
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 392 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0165-4608
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The karyotypes of 21 patients with chronic B cell leukemia were studied using lymphoblastoid cell lines obtained with the aid of the Epstein-Barr virus. Ten patients had a normal karyotype and eleven patients, an abnormal. There is no single characteristic anomaly, but certain types were more freque
In order to examine the role of Epstein-Barr virus (EBV) in the pathogenesis of chronic active EBV infection (CAEBV), we investigated whether or not EBV integration into the human genome is associated with any chromosonal abnormality. We therefore analyzed 4 cases of CAEBV: 2 cases showed a normal k