Chromosome aberrations induced in the lymphocytes of pilots and stewardesses
β Scribed by W. Scheid; J. Weber; H. Traut; H. W. Gabriel
- Publisher
- Springer
- Year
- 1993
- Tongue
- English
- Weight
- 318 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0028-1042
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π SIMILAR VOLUMES
Peripheral blood lymphocytes from three patients with Down syndrome (DS; trisomy 21; aged 5-6 years) and three age-matched control children were studied for the induction of chromosomal aberrations and sister chromatid exchanges (SCEs). Cells in G0 were exposed to bleomycin (20-100 micrograms/ml) fo
## Abstract Unstimulated lymphocytes from individuals with Down Syndrome (trisomy 21) are more sensitive to the induction of dicentric and ring aberrations by X rays than normal lymphocytes. Several explanations involving the more rapid rejoining of Xβrayβinduced lesions in Down cells have been off