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Chromosome 1 abnormalities in hepatocellular carcinoma

✍ Scribed by Martin Werner; Martina Nolte; Axel Georgii; Jürgen Klempnauer


Book ID
119105969
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
86 KB
Volume
66
Category
Article
ISSN
0165-4608

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Recurrent chromosomal abnormalities in h
✍ Agnès Marchio; Mounira Meddeb; Pascal Pineau; Gisèle Danglot; Pierre Tiollais; A 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 580 KB

Comparative genomic hybridization (CGH) was used to evaluate and map genomic aberrations in 50 hepatocellular carcinomas (HCCs) from patients chronically infected with hepatitis B virus (HBV). CGH clearly detected nonrandom genomic imbalances. Losses were most prevalent on chromosome regions 4q (70%