Chromosomal abnormality in hepatocellular carcinoma by comparative genomic hybridisation in Taiwan
β Scribed by Y.-W Lin; J.-C Sheu; G.-T Huang; H.-S Lee; C.-H Chen; J.-T Wang; P.-H Lee; F.-J Lu
- Book ID
- 117666118
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 120 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0959-8049
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Comparative genomic hybridization (CGH) was used to evaluate and map genomic aberrations in 50 hepatocellular carcinomas (HCCs) from patients chronically infected with hepatitis B virus (HBV). CGH clearly detected nonrandom genomic imbalances. Losses were most prevalent on chromosome regions 4q (70%
## Nasopharyngeal carcinoma (NPC) is a common cancer in Southern China but rare in Western countries. To search for genetic alterations in NPC, we examined a series of 20 primary tumours with comparative genomic hybridisation. The identified common chromosomal alterations included gain of chromoso