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Chromosomal transmission of human herpesvirus 6 DNA in acute lymphoblastic leukaemia

โœ Scribed by Masanori Daibata; Takahiro Taguchi; Taeko Sawada; Hirokuni Taguchi; Isao Miyoshi


Book ID
117297963
Publisher
The Lancet
Year
1998
Tongue
English
Weight
160 KB
Volume
352
Category
Article
ISSN
0140-6736

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In classical t(9;22) translocation, as observed in chronic granulocytic leukemia (CGL), a hybrid DNA unit is produced, including a rearranged PHL gene, previously known as bcr (breakpoint cluster region) plus the translocated c-abl gene from chromosome 9: a hybrid bcr-abl protein, p210 is formed, wi