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Chromosomal Translocations in Lymphoid Malignancies Reveal Novel Proto-Oncogenes

✍ Scribed by Korsmeyer, S J

Book ID
125430285
Publisher
Annual Reviews
Year
1992
Tongue
English
Weight
897 KB
Volume
10
Category
Article
ISSN
0732-0582

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Deletion of the short arm of chromosome 9 (9p), resulting in the loss of the p16 INK4a /MTS1 gene, now called CDKN2, has been found to occur frequently in acute lymphoblastic leukemia, even in the absence of a microscopically visible deletion. In this study, we have used YAC probes encompassing the