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Chromosomal organization of viral integration sites in human papillomavirus-immortalized human keratinocyte cell lines

✍ Scribed by D.B. Zimonjic; N.D. Popescu; J.A. DiPaolo

Book ID
119106128
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
486 KB
Volume
72
Category
Article
ISSN
0165-4608

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Human papillomavirus (HPV) types I 6 and 18 integration sites were mapped in six HPV-immortalized human keratinocyte cell lines by fluorescence in situ hybridization (FISH). Mapping of HPV sequences in these cell lines revealed that HPV integration varied in copy number and location but that integra