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Chromosomal mosaicism and maternal cell contamination in chorionic villi cultures

โœ Scribed by Bernt Schulze; Konstantin Miller


Book ID
115089422
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
115 KB
Volume
30
Category
Article
ISSN
0009-9163

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In 3,000 chorionic villi studies (CVS) 33 cases of mosaicism and 7 false-positive cell lines in all cells were seen. The mosaic cell lines were caused by aneuploidy of autosomes (13x), sex chromosomes (9x), and structural anomalies (11x1. Mosaics of fetal origin were only 4 cases of trisomy 21 and o