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An evaluation of maternal cell contamination in cultures of chorionic villi for the prenatal diagnosis of chromosome abnormalities

✍ Scribed by Heather M. G. Cooke; Richard J. A. Penketh; Joy D. A. Delhanty


Book ID
115089535
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
604 KB
Volume
30
Category
Article
ISSN
0009-9163

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Fetal erythroblasts circulating in maternal blood are important candidate cells for non-invasive prenatal diagnosis. We have cultured erythroblasts from 16 maternal blood samples, both with and without prior enrichment by magnetic activated cell sorting (MACS), in a semi-solid medium containing grow