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Chromosomal Localization of Putative Tumor-Suppressor Genes in Several Human Cancers

✍ Scribed by Jun Yokota, Takashi Sugimura and Masaaki Terada


Book ID
124310833
Publisher
Environmental Health Information Service
Year
1991
Tongue
English
Weight
211 KB
Volume
93
Category
Article
ISSN
0091-6765

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## Abstract Loss of heterozygosity on the long arm of chromosome 16 is one of the most frequent genetic events in breast cancer, suggesting the presence of one or more classic tumor‐suppressor genes (TSGs). It has been shown that E‐cadherin is the TSG on 16q in lobular tumors. In a search for the t