Chromosomal integration of adeno-associated parvovirus DNA limits proliferation and dispersal of human MKr melanoma cells in co-cultures with human fibroblasts

Integration of adeno-associated virus 2

Integration of adeno-associated virus 2 DNA in human MKR melanoma cells induces a peptide with oncosuppressive properties

✍ Ursula Bantel-Schaal 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 495 KB

Integration of adeno-associated virus type 2 (AAV2) DNA into the genome of the human MKr melanoma cell line grossly alters the cellular phenotype of these cells. Cultures derived from AAV DNA-harboring single cells share various similarities with normal cells in culture, and a considerable number of