We report on a patient with multiple congenital anomalies and ring chromosome 22 who died at age 16 years of bronchopneumonia. Autopsy documented multiple psammomatous meningiomas of the spinal dura and tentorium. n m o r tissue for cytogenetic analysis was not available. Although abnormalities of c
Chromosomal Constitution of Meningiomas
โ Scribed by ZANG, K. D.; SINGER, H.
- Book ID
- 109659714
- Publisher
- Nature Publishing Group
- Year
- 1967
- Tongue
- English
- Weight
- 250 KB
- Volume
- 216
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/216084a0
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We describe a patient who developed multiple meningiomas but had no clear evidence of neurofibromatosis type 2. Four of the tumors, derived from three different sites, were analyzed cytogenetically and/or at the DNA level using chromosome 22 specific probes. All four tumors showed loss of the same c
## Abstract Cytogenetic studies of eight meningiomas in young children or adolescents were performed. Two tumors exhibited normal karyotypes. Two tumors from patients with bilateral acoustic neurofibromatosis demonstrated monosomy 22 as the only abnormality. Four patients had more complicated karyo